Therapeutic Angiogenesis in Diabetes and Hypercholesterolemia: Influence of Oxidative Stress
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چکیده
منابع مشابه
Oxidative stress in angiogenesis and vascular disease.
Despite the damaging effect on tissues at a high concentration, it has been gradually established that oxidative stress plays a positive role during angiogenesis. In adults, physiological or pathological angiogenesis is initiated by tissue demands for oxygen and nutrients, resulting in a hypoxia/reoxygenation cycle, which, in turn promotes the formation of reactive oxygen species (ROS). The ROS...
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Objective(s): Long-term, irregular endurance exercise may result in disturbance to the angiogenesis of heart muscles and blood supply. The aim of the present study is to evaluate the effects of mid- and long-term endurance exercise on the process of angiogenesis.Materials and Methods: Eighteen male Wister rats of 220±10 g, were randomly assigned to three groups of 6 rats including: Control, Mid...
متن کاملDiabetes and Oxidative Stress: The Mechanism and Action
Abstract Diabetes mellitus is one of the major metabolic disorders. Diabetes is recognized for severe complications including diabetic nephropathy, neuropathy and retinopathy. Long-lasting effect of hyperglycemia results in increased oxidative stress. Oxidative stress results from an imbalance between radical-generating and radical scavenging systems. Increased oxidative stress has been shown ...
متن کاملHypercholesterolemia, oxidative stress and gender dependence in children.
Hypercholesterolemia (HCH) is characterized by an increase of the total- and LDL-cholesterol in serum. In hypercholesterolemia, generally recognized as a risk factor of atherogenesis, oxidative stress and oxidatively modified LDL play a crucial role. In our study, children with elevated total cholesterol (above 4.5 mmol/l) were included. Parameters of lipid profile, lipophilic vitamins and anti...
متن کاملOxidative stress , F - isoprostanes and endothelial dysfunction in 2 hypercholesterolemia
See article by Wilson et al. [9] (pages 601 –607) in this attenuated by pretreatment with L-arginine or the NO issue. donor NOR-3. These observations suggest a tonic vasoconstrictor activity dynamically opposed by NO, with the net vasomotor effect resulting from the balance of the two
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ژورنال
عنوان ژورنال: Antioxidants & Redox Signaling
سال: 2009
ISSN: 1523-0864,1557-7716
DOI: 10.1089/ars.2009.2439